DCI and Other Vitamins and Minerals

DCI and Other Vitamins and Minerals

Posted on Apr 11th 2020 | By: Sally S

Like most vitamins and minerals, DCI is safe when taken in reasonable amounts.

 And since it is water-soluble, what you don't use is excreted, making it even safer than some other supplements.

If you've ever taken a multivitamin, you know that it is fine to take several vitamins together in the same pill at the same time; that is what a multivitamin is. DCI is no exception. You can take it just like you would any other vitamin.

If after reading this article you still have a question, you can submit it via the contact form. Don't be shy. Sometimes we get really great questions that can help us to improve our knowledge base articles

Vitamin D

We frequently get questions regarding vitamin D and DCI. This is likely because vitamin D is a very common supplement in the PCOS community. Many PCOS women have low vitamin D1 and supplementation has been shown to have benefits for women with PCOS.2 If you have PCOS and you're not taking vitamin D, you should seriously consider adding it to your regimen. And, just to be clear, it is absolutely fine to take D-chiro-inositol along with a vitamin D supplement. If you're not already taking extra vitamin D, consider trying our Tri Sense product. [read more about vitamin D and Polycystic Ovarian Syndrome]

B Vitamin Complex

The B vitamin complex includes B6 and B12, which are usually just referred to by those abbreviations; their actual names are long and there are multiple forms of both B6 and B12. There are many other B vitamins that are usually referred to by their name. These include thiamine (B1), riboflavin (B2), niacin (B3), pantothenic acid (B5), biotin (B7) and folate (B9). It is fine take any and all of the B vitamins along with DCI, which is itself vitamin B8. [read more about the B vitamin complex and Polycystic Ovarian Syndrome]


Perhaps because they look a little bit alike when written, manganese and magnesium are sometimes confused. It is very important to recognize that manganese and magnesium are different things. Not only is manganese safe to take with D-chiro-inositol, it has been shown in animal studies to greatly improve the efficacy of DCI.3 However, manganese should always be taken in reasonable amounts (typically 1.8-2 mg daily). Too much manganese can compete with other minerals for absorption. Most daily multivitamins have an appropriate amount. But, if your multi doesn't or if you're not taking a multi, consider trying our Tri Sense product. [read more about manganese and Polycystic Ovarian Syndrome]


Insulin resistance is a common issue with PCOS. And the function of both chromium and D-chiro-inositol, in the simplest sense, is to support insulin sensitivity. So, as with manganese, chromium is not just safe to take with DCI, but something we recommend. It is found in many multivitamins, but if you aren't taking chromium presently, consider adding Tri Sense to your daily routine. [read more about chromium and Polycystic Ovarian Syndrome]


  1. Li HW, Brereton RE, Anderson RA, Wallace AM, Ho CK. Vitamin D deficiency is common and associated with metabolic risk factors in patients with polycystic ovary syndrome. Metab Clin Exp. 2011;60(10):1475-81. http://www.ncbi.nlm.nih.gov/pubmed/21550088
  2. Kotsa K, Yavropoulou MP, Anastasiou O, Yovos JG. Role of vitamin D treatment in glucose metabolism in polycystic ovary syndrome. Fertil Steril. 2009;92(3):1053-8. http://www.ncbi.nlm.nih.gov/pubmed/18930208
  3. Fonteles MC, Almeida MQ, Larner J. Antihyperglycemic effects of 3-O-methyl-D-chiro-inositol and D-chiro-inositol associated with manganese in streptozotocin diabetic rats. Horm Metab Res. 2000;32(4):129-32. http://www.ncbi.nlm.nih.gov/pubmed/16730719